Clinical uses of riboflavin in pediatrics: migraines, Autism Spectrum Disorder, and beyond

What is riboflavin? Riboflavin, or vitamin B2, is a water-soluble B vitamin that plays a central role in cellular metabolism, mitochondrial function, and redox homeostasis. Biochemically, riboflavin is the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), both of which are essential for the activity of a wide range of flavoproteins […]
Clinical use of vitamin B6 – ASD, ADHD, PMS and mood disorders

What is the function of vitamin B6? Vitamin B6 is a water-soluble vitamin known as pyridoxine. The active coenzyme forms of vitamin B6 are called pyridoxal-5-phosphate (PLP) and pyridoxamine 5 phosphate (PMP). Vitamin B6 performs a wide variety of functions throughout the body in these active coenzyme forms. It is involved in over 100 enzymatic […]
Peppermint for functional abdominal pain in children

Introduction Functional abdominal pain disorders (FAPDs) in children and adolescents present a complex clinical challenge within the realm of pediatric medicine, characterized by chronic abdominal pain and multifaceted diagnostic criteria. These disorders encompass a spectrum of conditions such as functional dyspepsia, irritable bowel syndrome, abdominal migraine and FAP-not otherwise specified, each exhibiting distinctive symptom patterns. […]
Quercetin supplementation for children: safety, research and efficacy

What is Quercetin? Quercetin is a plant pigment found in a variety of fruits, vegetables, nuts, and grains. Quercetin is a bioflavonoid known as a flavonol, important for its antioxidant properties.1 Its antioxidant properties help neutralize free radicals that may otherwise cause inflammation and contribute to a wide range of chronic diseases. Quercetin is best […]
Clinical uses of L-tyrosine in naturopathic medicine

What is Tyrosine and what is it used for? L-Tyrosine, commonly referred to as just tyrosine, is a conditionally essential amino acid that the body makes from another amino acid, phenylalanine. Tyrosine is essential for the production of a family of neurotransmitters called catecholamines that includes epinephrine, norepinephrine, and dopamine.1 Additionally, tyrosine is a precursor […]
Thiamine (vitamin B1) deficiency and supplementation in children

What is thiamine? Thiamine, or vitamin B1, is a water soluble vitamin found naturally in some foods and added to others. All of the B vitamins are essential for energy production because they help convert carbohydrates to glucose, the body’s primary fuel source. Thiamine is important for nutrient metabolism, a healthy liver, skin, hair, eye […]
The evidence for CoQ10 supplementation in children

What is Coenzyme Q10 (CoQ10) and what does it do? Coenzyme Q10 (CoQ10) is a fat soluble compound synthesized in the body. It is commonly referred to as ubiquinone because it is found in almost every cell in all living organisms, making it ubiquitous in nature. CoQ10 is found in the mitochondrial membrane where it […]
Copper deficiency, toxicity and supplementation in children

Copper is a mineral found in all body tissues and most secretions. It serves as a cofactor for enzymes involved in energy production, iron metabolism, and neurotransmitter synthesis.1 Additionally, copper is a cofactor for superoxide dismutase, an important part of the body’s antioxidant defense against oxidative stress. Copper is necessary for the synthesis of connective […]
5-hydroxytryptophan (5-HTP) and the “feel good” neurotransmitter serotonin

What is 5-HTP? 5-hydroxytryptophan (5-HTP) is a chemical the body makes from tryptophan, an amino acid found in food. After tryptophan is converted to 5-HTP it is converted again, but this time to serotonin. Serotonin is a neurotransmitter that carries messages from the brain to various parts of the body and plays a role in […]
The fine line between Elimination Diets and Eating Disorders

As a pediatric naturopathic doctor I have over ten years of experience using therapeutic elimination diets in children. I have seen many cases of dramatic reversal of chronic disease or behavior concerns. That said, in the last few years I have found myself increasingly hesitant to recommend restrictive diets, especially as elimination diets have exploded […]